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recombinant rat dickkopf 1 dkk 1 protein  (R&D Systems)


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    R&D Systems recombinant rat dickkopf 1 dkk 1 protein
    Recombinant Rat Dickkopf 1 Dkk 1 Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 30 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant rat dickkopf 1 dkk 1 protein/product/R&D Systems
    Average 93 stars, based on 30 article reviews
    recombinant rat dickkopf 1 dkk 1 protein - by Bioz Stars, 2026-03
    93/100 stars

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    Experimental protocol diagram. Forty-eight male SD rats were randomly divided into 4 groups (n = 12 each): Sham, I/R, Q and Q+DKK group. At 30 min before ischemia/reperfusion (red arrow), intracerebroventricular injections were performed. <t>DKK-1</t> and NS were given respectively. At 24 h after reperfusion, neurological assessment of the rats was performed using NDS. Then the rats were sacrificed and the brains were harvested for HE staining, NeuN staining and detection of brain water content (BWC). BBB ultrastructure and permeability were examined by transmission electron microscopy (TEM) and Evans blue (EB) extravasation, respectively. Western blot, RT-PCR and immunohistochemical analysis were performed for the relevant key factors of Wnt signaling pathway.
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    Experimental protocol diagram. Forty-eight male SD rats were randomly divided into 4 groups (n = 12 each): Sham, I/R, Q and Q+DKK group. At 30 min before ischemia/reperfusion (red arrow), intracerebroventricular injections were performed. DKK-1 and NS were given respectively. At 24 h after reperfusion, neurological assessment of the rats was performed using NDS. Then the rats were sacrificed and the brains were harvested for HE staining, NeuN staining and detection of brain water content (BWC). BBB ultrastructure and permeability were examined by transmission electron microscopy (TEM) and Evans blue (EB) extravasation, respectively. Western blot, RT-PCR and immunohistochemical analysis were performed for the relevant key factors of Wnt signaling pathway.

    Journal: American Journal of Translational Research

    Article Title: Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway

    doi:

    Figure Lengend Snippet: Experimental protocol diagram. Forty-eight male SD rats were randomly divided into 4 groups (n = 12 each): Sham, I/R, Q and Q+DKK group. At 30 min before ischemia/reperfusion (red arrow), intracerebroventricular injections were performed. DKK-1 and NS were given respectively. At 24 h after reperfusion, neurological assessment of the rats was performed using NDS. Then the rats were sacrificed and the brains were harvested for HE staining, NeuN staining and detection of brain water content (BWC). BBB ultrastructure and permeability were examined by transmission electron microscopy (TEM) and Evans blue (EB) extravasation, respectively. Western blot, RT-PCR and immunohistochemical analysis were performed for the relevant key factors of Wnt signaling pathway.

    Article Snippet: China), and rat DKK-1 (4010-DK-010) recombinant protein (1341-WF-050) from R&D System (Minnesota, USA).

    Techniques: Staining, Permeability, Transmission Assay, Electron Microscopy, Western Blot, Reverse Transcription Polymerase Chain Reaction, Immunohistochemical staining